THE QUESTION:

What was the biblical "thorn in the flesh" that so plagued St. Paul?

THE RELIGION GUY'S ANSWER:

We'll never be sure. But the question is perennially fascinating.

"Thorn in the flesh" is one of many commonplace phrases we take from the Bible. It appears in 2 Corinthians chapter 12, where St. Paul writes that he knew "a man" -- modestly referring to himself -- who was "caught up into Paradise and heard things that are not to be told." He describes the aftermath of his powerful experience in verses 7-9:

To keep me from being too elated, a thorn was given me in the flesh, a messenger of Satan to torment me, to keep me from being too elated. Three times I appealed to the Lord about this, that it would leave me, but he said to me, “My grace is sufficient for you, for power is made perfect in weakness.” So, I will boast all the more gladly of my weaknesses, so that the power of Christ may dwell in me. (New Revised Standard Version)

Other English translations say "arrogant," "conceited," "lifted up," "proud" or "exalted" instead of "elated."

Christians through history have pondered what so plagued this New Testament writer and Christian founder (though we can imagine his close colleagues knew). Some say it was a interior spiritual or psychological challenge, while others see opponents, obstacles or persecution his pioneer missionary work coped with.

Many focus on the telltale word "flesh" and insist it must have been some physical malady.